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College of Food, Agricultural, and Environmental Sciences


Hanping Wang, PhD

Hanping Wang, PhD
Principal Scientist and Director - Aquaculture Research and Development
1864 Shyville Road, Piketon, OH 45661


Research Interests:

Genomics/Genetics; Epigenetics; Sex-control and sex determination mechanism; Selective breeding; Immune-relevant genes and their relation to stress.

Grants/Projects as the Principal Investigator:

Number of Federal and State Grants as the Principal Investigator 49 ($8,701,172)

Number of Grants from other countries and international organizations 16 ($235,282)

Number of projects as the Principal Investigator 65 ($8,937,000)

Selected Publications (past 10 years; of >100; * indicate student co-author):


Wang, H.P., F. Piferrer and S.L. Chen. 2018. Sex Control in Aquaculture. Wiley-Blackwell .

Liang, X.F., H.P. Wang, H. Liu and R.W. Hardy. 2018. World Perch and Bass Culture: Innovation and Industrialization. China Science Press. Beijing

Book Articles:

Wang, H. P., Z. G. Shen, H. Yao, P. O’Bryant, and D. Rapp. 2018. Sex determination and monosex female production in yellow perch. In: Sex Control in Aquaculture: (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

Wang, H. P., Z. G. Shen, Z.X. Gao, H. Yao, D. Rapp, and P. O’Bryant. 2018. Sex Determination, Differentiation, and Control in Bluegill. In: Sex Control in Aquaculture: Theory and Practice (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

Wang, H.P., and Z.G. Shen. 2018. Sex Control in Aquaculture: Concept and Practice. In: Sex Control in Aquaculture (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

Wang, H. P., and X.J. Cao. 2018. Selective Breeding of Yellow Perch. In: World Perch and Bass Culture: Innovation and Industrialization (Liang, X.F., H.P. Wang, H. Liu and R.W. Hardy Ed.). China Science Press. Beijing.

*Liang,H.W., H.P. Wang, Y.M, H. Yao, Z.G. Shen, and G.W. Zou. 2018. Sexual dimorphism in body size and form in yellow perch. In: Sex Control in Aquaculture (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

*Shen Z.G. and H.P. Wang. 2018. Environmental sex determination and sex differentiation in teleost – How sex is established. In: Sex Control in Aquaculture (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

*Shen Z.G. and H.P. Wang. 2017. Hybridization and its application in Centrarchids. In: Sex Control in Aquaculture (Wang, H.P., F. Piferrer & S.L. Chen Ed.). Wiley-Blackwell.

Vikas, K., A. K. Sinha, H. P. Wang, and Gudrun de Boeck. 2014. Fibre and gastrointestinal health. In: Advanced Nutrition and Dietetics in Gastroenterology (Miranda Lomer Ed.). Wiley-Blackwell.

Peer-Reviewed Scientific Journal (past 10 years; of >100):

Hiam Elabd, Han-Ping Wang, Adel Shaheen, Aya Matter. 2020. Astragalus membranaceus nanoparticles markedly improve immune and anti-oxidative responses; and protection against Aeromonas veronii in Nile tilapia Oreochromis niloticus. Fish & Shellfish Immunology Volume 97, February 2020, Pages 248-256

*Dan Wang, Hong Yao, Yan-He Li, Yong-Jiang Xu, Xu-Fa Ma, Han-Ping Wang. 2019. Global diversity and genetic landscape of natural populations and hatchery stocks of largemouth bass micropterus salmoides across American and Asian regions. Scientific Reports. 9, 16697 (2019) doi:10.1038/s41598-019-53026-3

*Liang Guo, Hong Yao, Brian Shepherd, Osvaldo J. Sepulveda-Villet, Dian-Chang Zhang, Hanping Wang. 2019. Development of a Genomic Resource and Identification of Nucleotide Diversity of Yellow Perch by RAD Sequencing. Front. Genet., 14 October 2019

Xie P, Yi S-K, Yao H, Chi W, Guo Y, Ma XF, and Wang HP. 2019. Comparative transcriptome analysis reveals potential evolutionary differences in adaptation of temperature and body shape among four Percidae species. PLoS ONE 14(5): e0215933.

*Eman A. Abd El-Gawad, Hanping Wang, Hong Yao. 2019. Diet Supplemented With Synthetic Carotenoids: Effects on Growth Performance and Biochemical and Immunological Parameters of Yellow Perch (Perca flavescens). Front. Physiol., 21 August 2019

*Shen Z-G, Eissa N, Yao H, Xie Z-G and Wang H-P. 2018. Effects of Temperature on the Expression of Two Ovarian Differentiation-Related Genes foxl2 and cyp19a1a. Front. Physiol. 9:1208. doi: 10.3389/fphys.2018.01208

*Eissa, N., H. P. Wang, H. Yao, E. A. ElGheit, A. A. Shaheen. 2018. A Mixed Bacillus Species Enhances the Innate Immune Response and Stress Tolerance of Yellow Perch Subjected to Hypoxia and Air Exposure Stress. Scientific Reports, DOI: 10.1038/s41598-018-25269-z

*Li Y-H, Wang H-P, Yao H, O’Bryant P, Rapp D, Guo L, et al. 2017.  De novo transcriptome sequencing and analysis of male, pseudo-male and female yellow perch, Perca flavescens. PLoS ONE 12(2): e0171187. doi:10.137 1/journal.pone .0171187

*Li, Y. H. and H. P. Wang. 2017. Advances of genotyping-by-sequencing in fisheries and aquaculture. Review in Fish Biology and Fisheries. DOI: 10.1007/s11160-017-9473-2.

Abdelrahman… and H. P. Wang et al. 2017. Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research. BMC Genomics 18:191. DOI 10.1186/s12864-017-3557-1

*Shen, Z.G. H. Yao, L. Guo, X.X. Li, and H.P. Wang. 2017. Ribosome RNA Profiling to Quantify Ovarian Development and Identify Sex in Fish. Scientific Reports, doi:10.1038/s41598-017-04327-y

*Eissa N, Wang H-P, Yao H, Shen Z-G, Shaheen AA and Abou-ElGheit EN. 2017. Expression of Hsp70, Igf1, and Three Oxidative Stress Biomarkers in Response to Handling and Salt Treatment at Different Water Temperatures in Yellow Perch, Perca flavescens. Front. Physiol. 8:683. doi: 10.3389/fphys.2017.00683.

*Elabd,H., H. P. Wang, A. A. Shaheen, H. Yao, and A. Abbass. 2017. Anti-oxidative effects of some dietary supplements on Yellow perch (Perca flavescens) exposed to different physical stressors. Aquaculture Reports. 8: 61-88,

*Shen, Z. G, H. P. Wang, H. Yao, P. O’Bryant1, D. Rapp1, and K. Q. Zhu. 2016. Sex determination in bluegill sunfish: Effect of temperature on sex ratio of four geographic strains. The Biological Bulletin. 230:197-208

*Hiam Elabd, Han-Ping Wang, Adel Shaheen, Hong Yao and Amany Abbass . 2016. Feeding Glycyrrhiza glabra (liquorice) and Astragalus membranaceus (AM) alters innate immune and physiological responses in yellow perch (Perca flavescens). Fish & Shellfish Immunology. 54: 374-384. ISSN 1050-4648.

*Hiam Elabd, Han-Ping Wang, Adel Shaheen, Hong Yao and Amany Abbass . 2016. Astragalus membranaceus (AM) enhances growth performance and antioxidant stress profiles in bluegill sunfish (Lepomis macrochirus). Fish physiology and biochemistry. 1–12. doi:10.1007/s10695-015-0188-9.

*Waly, E. A., Z. G, Shen, and H. P. Wang. 2016. Efficacy of formalin, iodine and sodium chloride in improvement of egg hatching rate and fry survival prior to the onset of exogenous feeding in yellow perch. Aquaculture Research, 1-9. doi:10.1111/are.12694.

*Shen, Z. G, Q. X. Fan, W. Yang, Y. L. Zhang, and H. P. Wang. 2015. Effects of 17β-Methyltestosterone and Aromatase Inhibitor Letrozole on Sex Reversal, Gonadal Structure, and Growth in Yellow Catfish Pelteobagrus fulvidraco. The Biological Bulletin, 228: 108–117.

Wang, H.P. M. L. Aslam, H. Yao, D. Rapp, P. O’Bryant. 2014. Genetic variability pattern of yellow perch over six generations of marker-aided cohort selection for growth. Proceedings of 10th World Congress of Genetics Applied to Livestock Production. 1-3.

*Eissa, N., and H. P. Wang. 2014. Transcriptional Stress Responses to Environmental and Husbandry Stressors in Aquaculture Species. Reviews in Aquaculture. DOI: 10.1111/raq.12081.

Wang, H.P., Z. Gao, P. O'Bryant, J. D. Rapp, H. Yao, Xiao-juan Cao. 2014. Temperature effects and genotype-temperature interactions on sex determination in bluegill Lepomis macrochirus. Aquaculture. Volumes 420–421: S64–S71 (PDF)

*Shen, Z.G. and H.P. Wang. 2014. Molecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fish. Genet Sel Evol, 2014, 46:26.(PDF)

*Eissa, N. and H.P. Wang. 2013. Physiological stress response of yellow perch subjected to repeated handlings and salt treatments at different temperatures. North American Journal of Aquaculture 75:449–454. (PDF)

*Cao, X, H.P. Wang, H. Yao, P. O'Bryant, J. D. Rapp and G. K. Wallat. 2012. Evaluation of one-stage and two-stage selection in yellow perch I: genetic and phenotypic parameters for growth traits of F1 fish reared in ponds using microsatellite parentage. Journal of Animal Sciences 90:27–36. (PDF)

*Xu, Y.J., X.Z. Liu, M.J. Liao, H.P. Wang, and Q.Y. Wang. 2012. Molecular Cloning and Differential Expression of Three GnRH Genes during Ovarian Maturation of SpottedHalibut, Verasper variegates. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 317:434-446. (PDF)

Wang, H.P., H. Yao, P. O’Bryant, D. Rapp, G.K. Wallat and R. MacDonald. 2011. Family-tank interactions on early growth performance of yellow perch reared in single family tanks versus mixed-family tanks as inferred using molecular pedigrees. Aquaculture research 42:1694-1702. (PDF)

*Gao, Z., H.P. Wang, H. Yao, W. Wang and L.G. Tiu. 2010. No sex-specific markers detected in bluegill sunfish Lepomis macrochirus by AFLP. Journal of Fish Biology, 76: 408 - 414. (PDF)

*Wang , W.J., H.P. Wang, H.Yao, G.K. Wallat, L.G. Tiu, and Q.Y. Wang. 2010. A first genetic linkage map of bluegill sunfish (Lepomis macrochirus) using AFLP markers. Aquaculture International, 18:825–835. (PDF)

*Gao, Z., H.P. Wang, G.K. Wallat, H. Yao, D. Rapp, P. O’Bryant, R. MacDonald and W. Wang, 2010. Effects of a nonsteroidal aromatase inhibitor on sex reversal, gonadal differentiation and growth performance of bluegill sunfish Lepomis macrochirus. Aquaculture research, 41: 1282-1289. (PDF)

*Cao, X, H. P. Wang, H. Yao, W. M. Wang, P. O’Bryant and D. Rapp. 2010. Correlations between Growth Traits and Heterozygosity, Allelic Distance (d2) at microsatellite Loci in the Yellow Perch, Perca flavescens. Journal of Biotechnology 150:2-3. (PDF)

Wang, H.P., L. Li, G.K. Wallat, B. Brown, H. Yao, Z. Gao L.G. Tiu, P. O’Bryant, D. Rapp and R. MacDonald. 2009. Evaluation of relative growth performance and genotype by environment effects for cross-bred yellow perch families reared in communal ponds using DNA parentage analyses. Aquaculture Research, 40: 1363 - 1373. (PDF)

*Gao, Z., H.P. Wang, D. Rapp, P. O’Bryant, H. Yao, G.K. Wallat, W. Wang, R. MacDonald and L.G. Tiu. 2009. Gonadal sex differentiation in the bluegill sunfish Lepomis macrochirus and its relation to fish size and age. Aquaculture, 294:138–146. (PDF)

Wang, H.P. G.K. Wallat, R. Hayward, P. L.G. Tiu, O’Bryant and D. Rapp. 2009. Establishment of mostly-male groups of bluegill by size-selection and evaluation of their growth performance. North American Journal of Aquaculture, 71:216–223. (PDF)

*Zhan, A.B, W. Yao, B. Brown, H.P. Wang, 2009. Isolation and characterization of novel microsatellite markers for yellow perch (Perca flavescens). International Journal of Molecular Science 10:18 – 27. (PDF)

Wang, H.P. Z. Gao, B. Beres, J. Ottobre, G.K. Wallat, L.G. Tiu, D. Rapp, P. O’Bryant and H. Yao. 2008. Effects of estradiol-17b on survival, growth performance, sex reversal and gonadal structure of bluegill sunfish Lepomis macrochirus. Aquaculture 285: 216–223 (PDF)

Brown, B., H. P Wang, L. Li, G. Chandler, and G.K. Wallat. 2007. Yellow perch strain evaluation I. Genetic variance of six broodstock populations. Aquaculture 271:142–151. (PDF)

*Li, L. H.P. Wang, C. Givens, and B. Brown. 2007. Isolation and characterization of microsatellites in the yellow perch (Perca flavescens). Molecular Ecology Notes 7: 600-603. (PDF)